|The CDKN1B cdkn1b (Catalog #MBS9200263) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CDKN1B Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CDKN1B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC).
WB~~1:1000. Researchers should empirically determine the suitability of the CDKN1B cdkn1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CDKN1B cdkn1b product has the following accession number(s) (GI #4757962) (NCBI Accession #NP_004055.1) (Uniprot Accession #P46527). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CDKN1B Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded H. skeletal muscle section using CDKN1B Antibody. MBS9200263 was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.)
Western Blot (WB) (Western blot analysis of lysates from MCF-7, U266 cell line (from left to right), using CDKN1B Antibody. MBS9200263 was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1- CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
Antigen Type: Recombinant Protein. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CDKN1B are readily searchable from our website. Different antibodies against the same target such as CDKN1B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Hyperplasia, Intestinal Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Experimental, Nervous System Diseases, Prostatic Neoplasms are some of the diseases may be linked to CDKN1B Antibody.