|The CDKN3 cdkn3 (Catalog #MBS532834) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CDKN3 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CDKN3 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Western Blot (WB).
WB: 1:2000. Researchers should empirically determine the suitability of the CDKN3 cdkn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CDKN3 cdkn3 product has the following accession number(s) (GI #17981704) (NCBI Accession #NP_005183) (Uniprot Accession #Q16667). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CDKN3 antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant CDKN3 protein (Right) or empty vector (Left) detected with CDKN3 antibody)
Mouse monoclonal CDKN3 antibody.
Biological Significance: CDKN3 belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Immunogen: CDKN3 antibody was raised in mouse using a full length recombinant protein of human CDKN3 (NP_005183) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CDKN3 are readily searchable from our website. Different antibodies against the same target such as CDKN3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adenocarcinoma, Breast Neoplasms, Carcinoma, Hepatocellular, Cell Transformation, Neoplastic, Liver Diseases, Liver Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to CDKN3 antibody. Blood, Brain, Embryonic Tissue, Heart, Liver, Lung, Mouth, Prostate, Stomach, Uterus tissues are correlated with this protein.