|The CEACAM6 ceacam6 (Catalog #MBS2544093) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human CEACAM6 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CEACAM6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA).
ELISA: 0.5-1 mug/mL. This antibody can be used at 0.5-1 mug/mL with the appropriate secondary reagents to detect Human CEACAM6/CD66c. The detection limit for Human CEACAM6/CD66c is approximately 0.00245 ng/well. Researchers should empirically determine the suitability of the CEACAM6 ceacam6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CEACAM6 ceacam6 product has the following accession number(s) (GI #612407822). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is an unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.
Immunogen: Recombinant Human CEACAM6/CD66c protein
Buffer: This antibody was obtained from a rabbit immunized with purified, recombinant Human CEACAM6 (rh CEACAM6; NP_002474.3; Met 1-Gly 320). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CEACAM6 are readily searchable from our website. Different antibodies against the same target such as CEACAM6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. CEACAM6 also interacts with the following gene(s): CEACAM1, CEACAM8, SRC. Bladder, Blood, Bone Marrow, Intestine, Lung, Pancreas, Prostate, Skin, Stomach, Trachea tissues are correlated with this protein.