|The CELSR3 celsr3 (Catalog #MBS606120) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CELSR3 (Cadherin EGF LAG Seven-pass G-type Receptor 3, Flamingo Homolog, hFmi1, Multiple epidermal growth factor-like domains 2, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CELSR3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the CELSR3 celsr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CELSR3 celsr3 product has the following accession number(s) (GI #145309304) (NCBI Accession #NP_001398.2) (Uniprot Accession #Q9NYQ7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Epidermal growth factor-like 1 belongs to the G-protein coupled receptor 2 family and the LN-TM7 subfamily. The unprocessed precursor has a length of 3312 amino acids and a predicted molecular weight of 358.3kD. It contains nine cadherin domains, eight EGF-like domains, one GPS domains, one laminin EGF-like domains and two laminin G-like domains. It is a transmembrane protein and is thought to have an important role in cell to cell signaling during nervous system formation.
Immunogen: Partial recombinant protein of human Epidermal growth factor-like 1 (aa71-180) with a GST tag. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CELSR3 are readily searchable from our website. Different antibodies against the same target such as CELSR3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adenocarcinoma, Carcinoma, Fibrosis, Inflammation, Liver Neoplasms, Lung Neoplasms are some of the diseases may be linked to CELSR3 (Cadherin EGF LAG Seven-pass G-type Receptor 3, Flamingo Homolog, hFmi1, Multiple epidermal growth factor-like domains 2, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2). Brain, Embryonic Tissue, Eye, Lung, Nerve, Skin, Testis tissues are correlated with this protein.