anti-CH25H antibody product blog
Tags: Antibody; CH25H; Monoclonal Antibody; anti-CH25H antibody;
The CH25H ch25h (Catalog #MBS6008745) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CH25H (Cholesterol 25-hydroxylase, Cholesterol 25-monooxygenase, h25OH) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CH25H can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the CH25H ch25h for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CH25H ch25h product has the following accession number(s) (GI #4502499) (NCBI Accession #NP_003947.1) (Uniprot Accession #O95992). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
WHLLHHKVPW LYRTFHKVHH QNSSSFALAT QYMSVWELFS LGFFDMMNVT LLGCHPLTTL TFHVVNIWLS VEDHSGYNFP WSTHRLVPFG WYGGVVHHDL HHSHFN.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CH25H (Cholesterol 25-hydroxylase, Cholesterol 25-monooxygenase, h25OH) with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis using MBS6008745 against Immunogen (37.66kD).)
Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
Immunogen: Partial recombinant corresponding to aa142-247 from CH25H (AAH17843.1) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CH25H are readily searchable from our website. Different antibodies against the same target such as CH25H may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CH25H also interacts with the following gene(s): CYP27A1, CYP46A1, CYP7B1, LIPA, SOAT1. Brain, Heart, Lung tissues are correlated with this protein. The following patways have been known to be associated with this gene. Brain Diseases, Cardiovascular Diseases, Fibrosis, Heart Diseases, Inflammation, Liver Diseases, Lung Diseases, Memory Disorders, Neoplasms, Nervous System Diseases are some of the diseases may be linked to CH25H (Cholesterol 25-hydroxylase, Cholesterol 25-monooxygenase, h25OH).