anti-CHD3 antibody product blog
Tags: Antibody; Monoclonal Antibody; CHD3; anti-CHD3 antibody;
The CHD3 chd3 (Catalog #MBS850786) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CHD3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s CHD3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS), ELISA (EIA).WB: 1:500-1:2000
IHC: 1:200-1:1000
IF: 1:200-1:1000
FC: 1:200-1:400
ELISA: 1:10000. Researchers should empirically determine the suitability of the CHD3 chd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CHD3 chd3 product has the following accession number(s) (GI #158420731) (NCBI Accession #NP_001005271.2) (Uniprot Accession #Q12873). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CHD3 Antibody with the following immunoassay(s):
Western Blot (WB) (Figure 1: Western blot analysis using CHD3 mouse mAb against Hela (1), K562 (2), Jurkat (3), NTERA-2 (4), HEK293 (5), Raji (6) cell lysate and mouse brain (7) tissue lysate.)
Immunohistochemistry (IHC) (Figure 2: Immunohistochemical analysis of paraffin-embedded colon cancer tissues using CHD3 mouse mAb with DAB staining.)
Immunofluorescence (IF) (Figure 3: Immunofluorescence analysis of Hela cells using CHD3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.)
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Immunogen: Purified recombinant fragment of human CHD3 expressed in E. Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CHD3 are readily searchable from our website. Different antibodies against the same target such as CHD3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CHD3 also interacts with the following gene(s): CHD4, HDAC1, HDAC2, MBD2, MTA1, MTA2, SUMO1. Autoimmune Diseases, Death, Fibrosis, Heart Diseases, Immune System Diseases, Inflammation, Musculoskeletal Diseases, Neoplasms, Nervous System Diseases are some of the diseases may be linked to CHD3 Antibody.