anti-CHIPS antibody product blog
Tags: Antibody; Monoclonal Antibody; CHIPS; anti-CHIPS antibody;
The CHIPS chp (Catalog #MBS584402) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s CHIPS can be used in a range of immunoassay formats including, but not limited to, FS, Immunoassay (IA), P, Western Blot (WB).Application Use: For immunohistology, Western blot and flow cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10 for flow cytometry and 1:100 for Western blot and immunohistology. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions. Researchers should empirically determine the suitability of the CHIPS chp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CHIPS chp product has the following accession number(s) (GI #156604074) (NCBI Accession #YP_001430019.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Product Description: The bacterial pathogen Staphylococcus aureus is insensitive to antimicrobial host defense peptides such as defensins, protegrins, platelet microbicidal proteins and bacteriocins. Staphylococci have developed various resistance mechanisms including those specific for bacteriocins and several host defense peptides. A protein belonging to the resistance mechanism of Staphylococcus aureus is known as CHIPS (Chemotaxis Inhibiting Protein of Staphylococcus aureus). CHIPS is a protein produced by Staphylococcus aureus that inhibits chemotaxis of neutrophils by blocking the Formyl Peptide Receptor (FPR) and C5a Receptor on neutrophils. CHIPS and antibodies against CHIPS can be useful for various experimental infection models of Staphylococcus aureus. Furthermore these reagents can be of help in studies on the role of FPR and C5a in inflammatory processes. Monoclonal antibody JCC1 reacts with the C-terminus of CHIPS.
In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CHIPS are readily searchable from our website. Different antibodies against the same target such as CHIPS may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.