|The CHUK chuk (Catalog #MBS532901) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CHUK antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CHUK can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunofluorescence (IF), Western Blot (WB).
WB: 1:500-1:2000. Researchers should empirically determine the suitability of the CHUK chuk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CHUK chuk product has the following accession number(s) (GI #1589738) (NCBI Accession #AAC50713.1) (Uniprot Accession #O15111). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CHUK antibody with the following immunoassay(s):
Western Blot (Western Blot analysis using CHUK antibody
Western Blot showing CHUK antibody used against Raji (1), Jurkat (2) and THP-1 (3) cell lysate.)
Mouse monoclonal CHUK antibody.
Biological Significance: CHUK is a member of the serine/threonine protein kinase family, CHUK is a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. Immunogen: CHUK antibody was raised in Mouse using a purified recombinant fragment of human CHUK expressed in E Coli as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CHUK are readily searchable from our website. Different antibodies against the same target such as CHUK may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Muscle, Skin tissues are correlated with this protein. Abnormalities, Multiple, Adenocarcinoma, Breast Neoplasms, Cell Transformation, Neoplastic, Heart Diseases, Inflammation, Liver Diseases, Liver Neoplasms, Necrosis, Skin Abnormalities are some of the diseases may be linked to CHUK antibody. CHUK also interacts with the following gene(s): AKT1, IKBKB, IKBKG, MAP4K4, NFKB1, NFKB2, NFKBIA, NFKBIB, RELA, TRAF2. The following patways have been known to be associated with this gene.