anti-CK19 / CYFRA21-1 antibody product blog
Tags: Antibody; Monoclonal Antibody; CK19 / CYFRA21-1; anti-CK19 / CYFRA21-1 antibody;
The CK19 / CYFRA21-1 n/a (Catalog #MBS355710) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Anti-CK19 / CYFRA21-1 (Capture Ab) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CK19 / CYFRA21-1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Chemilumineseent immunoassay (CLIA). Other applications have not been tested. The optimal dilutions should not be determined by end user.Capture Ab: CYFRA21-1 mAb (clone # D5); Detection Ab: CYFRA21-1 mAb (clone #C4). Researchers should empirically determine the suitability of the CK19 / CYFRA21-1 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Keratin, type I cytoskeletal 19 also known as cytokeratin-19 (CK-19) or keratin-19 (K19) is a 40 kDa protein that in humans is encoded by the KRT19 gene. KRT19 is also known as Cyfra 21-1. The usefulness of serum CYFRA 21-1 (cytokeratin-19 fragments) in monitoring the recurrence of breast cancer and in evaluating therapeutic effects. Serum CYFRA 21-1 may be a reliable marker of recurrence or therapeutic efficacy. The serum level of Cyfra21-1 was an useful biomarker for identification of nonsmall cell lung cancer (NSCLC) as well. The serum cytokeratin 19 fragment 21.1 (CYFRA21-1) level was elevated in nasopharyngeal carcinoma (NPC) and can function as a biomarker for detection and monitoring of NPC. After analyzing NPC group and healthy control group, Song XM et al concluded that the serum CYFRA21-1 level could be a reliable and effective biomarker for the detection and monitoring of NPC tumor progression.
Immunogen: 40 KDa of Keratin 19 protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CK19 / CYFRA21-1 are readily searchable from our website. Different antibodies against the same target such as CK19 / CYFRA21-1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.