anti-CTTN antibody product blog
Tags: Antibody; anti-Cttn antibody; Cttn; Monoclonal Antibody;
The CTTN cttn (Catalog #MBS850355) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CTTN Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s CTTN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA).WB: 1:500-1:2000
IHC: 1:200-1:1000
ELISA: 1:10000. Researchers should empirically determine the suitability of the CTTN cttn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CTTN cttn product has the following accession number(s) (GI #296080746) (NCBI Accession #NP_001171669.1) (Uniprot Accession #Q14247). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CTTN Antibody with the following immunoassay(s):
Western Blot (WB) (Figure 1: Western blot analysis using CTTN mouse mAb against Hela (1), A431 (2), MCF-7 (3), SR-BR-3 (4), HepG2 (5) and NIH/3T3 (6) cell lysate.)
Immunohistochemistry (IHC) (Figure 2: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues (left) and tonsil tissues (right) using CTTN mouse mAb with DAB staining.)
Testing Data
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. (provided by RefSeq).
Immunogen: Purified recombinant fragment of human CTTN expressed in E. Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CTTN are readily searchable from our website. Different antibodies against the same target such as CTTN may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CTTN also interacts with the following gene(s): ACTR3, FER, GRB2, HAX1, MET, PXN, SHANK2, SRC, SYK, TJP1. Blood, Bone, Brain, Embryonic Tissue, Kidney, Liver, Lung, Lymph Node, Muscle, Vascular tissues are correlated with this protein.