anti-CXCL1 antibody product blog
Tags: Antibody; Monoclonal Antibody; CXCL1; anti-CXCL1 antibody;
The CXCL1 cxcl1 (Catalog #MBS690237) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human CXCL1 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CXCL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Neutralization.WB: 1:500 - 1:1000
Neutralization of CXCL1 bioactivity. Researchers should empirically determine the suitability of the CXCL1 cxcl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CXCL1 cxcl1 product has the following accession number(s) (GI #4504153) (NCBI Accession #NP_038591.1) (Uniprot Accession #P34902). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Mouse Anti-Human CXCL1 with the following immunoassay(s):
Testing Data
Cotton rat growth-regulatedprotein (GRO) is a member of the ELR+ CXC subfamily of chemokines. The cotton rat GRO cDNA encodes a 100 amino acid (aa) precursor protein with a 27 aa putative signal peptide and a 73 aa mature protein. The predicted amino acid sequence of the mouse KC gene product indicates KC is a member of the CXC subfamily of chemokines. The protein sequence of mouse KC shows approximately 63% identity to that of mouse MIP-2. In addition, the protein sequence of KC is approximately 60% identical to the human GROs. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. KC mRNA is expressed in macrophages, endothelial cells, and fibroblasts.
Antigen: Human recombinant CXCL1
Preparation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant CXCL1 (also called GROa).
Reconstitution: Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml. Remarks: This antibody was selected for its ability to detect human CXCL1. It weakly reacts with CXCL2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CXCL1 are readily searchable from our website. Different antibodies against the same target such as CXCL1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Cardiovascular Diseases, Disease Models, Animal, Gastrointestinal Diseases, Inflammation, Lung Diseases, Lung Injury, Necrosis, Neoplasms, Pneumonia, Wounds and Injuries are some of the diseases may be linked to Mouse Anti-Human CXCL1.