anti-CYP1A1 antibody product blog
Tags: Antibody; CYP1A1; Monoclonal Antibody; anti-CYP1A1 antibody;
The CYP1A1 cyp1a1 (Catalog #MBS6012309) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CYP1A1, CT (CYP1A1, Cytochrome P450 1A1, CYPIA1, Cytochrome P450 form 6, Cytochrome P450-C, Cytochrome P450-P1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CYP1A1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in Western Blot, ELISA.
Dilution: ELISA: 1:1,000
Western Blot: 1:500~4000. Researchers should empirically determine the suitability of the CYP1A1 cyp1a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CYP1A1 cyp1a1 product has the following accession number(s) (GI #4503199) (NCBI Accession #NP_000490.1) (Uniprot Accession #P04798). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CYP1A1, CT (CYP1A1, Cytochrome P450 1A1, CYPIA1, Cytochrome P450 form 6, Cytochrome P450-C, Cytochrome P450-P1) with the following immunoassay(s):
Western Blot (WB) (CYP1A1 Antibody (C-term)(Ascites) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CYP1A1 antibody detected the CYP1A1 protein (arrow).)
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme\'s endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
Immunogen: CYP1A1 antibody is generated from mouses immunized with a KLH conjugated synthetic peptide between 377-406 amino acids from the C-terminal region of human CYP1A1. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CYP1A1 are readily searchable from our website. Different antibodies against the same target such as CYP1A1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.