anti-DCTN2 antibody product blog
Tags: Antibody; Monoclonal Antibody; DCTN2; anti-DCTN2 antibody; Dynamitin;
The DCTN2 dctn2 (Catalog #MBS2541899) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The DCTN2 Monoclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s DCTN2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA).WB: 1:200-1:2000
IHC: 1:20-1:200. Researchers should empirically determine the suitability of the DCTN2 dctn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The DCTN2 dctn2 product has the following accession number(s) (GI #387527972) (NCBI Accession #NP_001248341.1) (Uniprot Accession #Q13561). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the DCTN2 Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Human brain tissue using Dynamitin Monoclonal Antibody at dilution of 1:500)
Dynamitin is a 50 kDa protein containing a calmodulin binding domain, a putative ATPase domain and MacMARCKS-binding domain. This protein is a part of the dynactin complex believed to link the dynactin complex to membrane compartments. Its functions are tightly associated with dynein motor protein, thus extend to vesicle trafficking and membrane integrity. Dynamitin was named so because its overexpression causes dynactin complex which contains 10 subunits, to disassemble. Its N terminal 58 amino acid is for MacMARCKS binding and residues 59-83 is responsible for calmodulin binding. This antibody is is against the N terminal 86aa of full length p50 dynamitin.
Immunogen: Fusion protein of Dynamitin. Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation: Unconjugated. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DCTN2 are readily searchable from our website. Different antibodies against the same target such as DCTN2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adenocarcinoma, Breast Neoplasms, Neoplasms are some of the diseases may be linked to DCTN2 Monoclonal Antibody. Bone, Brain, Liver, Nerve, Spinal Cord tissues are correlated with this protein. The following patways have been known to be associated with this gene. DCTN2 also interacts with the following gene(s): GNAO1.