anti-Dkk-1 antibody product blog
Tags: Antibody; Monoclonal Antibody; Dkk-1; anti-Dkk-1 antibody;
The Dkk-1 dkk1 (Catalog #MBS690307) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human Dkk-1 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Dkk-1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the Dkk-1 dkk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The Dkk-1 dkk1 product has the following accession number(s) (GI #7110719) (NCBI Accession #NP_036374.1) (Uniprot Accession #O94907). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Dkk1 is a Dickkopf-related protein that inhibits Wnt signaling by binding the Wnt coreceptor LRP5/6. It also binds Kremen1 and Kremen2. Dkk1 is important in embryonic development.
Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant Dkk-1. Reconstitution: Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Dkk-1 are readily searchable from our website. Different antibodies against the same target such as Dkk-1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Dkk-1 also interacts with the following gene(s): CTNNB1, FZD1, FZD8, KREMEN1, KREMEN2, LRP5, LRP6, RSPO1, WNT1, WNT3A. The following patways have been known to be associated with this gene. Bone, Bone Marrow, Brain, Connective Tissue, Embryonic Tissue, Liver, Lung, Muscle, Skin, Vascular tissues are correlated with this protein. Adenocarcinoma, Brain Diseases, Breast Neoplasms, Cardiovascular Diseases, Hematologic Diseases, Inflammation, Necrosis, Neoplasm Metastasis, Neoplasms, Nervous System Diseases are some of the diseases may be linked to Mouse Anti-Human Dkk-1.