anti-DKK3 antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-DKK3 antibody; DKK3; Dickkopf-related protein 3;
The DKK3 dkk3 (Catalog #MBS147002) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti Human Dickkopf-Related Protein 3 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Dickkopf-Related Protein 3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the DKK3 dkk3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The DKK3 dkk3 product has the following accession number(s) (GI #66346689) (NCBI Accession #NP_001018067.1) (Uniprot Accession #Q9UBP4). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Dickkopf-related protein 3 (DKK3) belongs to the DKK protein family including Dkk-1, 2, 3 and-4. DKK3 is a 350 amino acid secreted glycoprotein which is comprised of an N-terminal signal peptide and 2 conserved cysteine-rich domains that are separated by a 12 amino acid linker region. DKK3 is involved in embryonic development through its inhibition of the WNT signaling pathway. DKK3 gene expression is decreased in a variety of cancer cell lines and it may act as a tumor suppressor gene.
Immunogen: Anti-human DKK3 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human DKK3 protein (22-350 amino acids purified from E Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DKK3 are readily searchable from our website. Different antibodies against the same target such as DKK3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Kidney, Lung, Muscle tissues are correlated with this protein. Adenocarcinoma, Breast Neoplasms, Carcinoma, Carcinoma, Hepatocellular, Liver Diseases, Lung Neoplasms, Neoplasms, Prostatic Neoplasms, Skin Diseases, Urinary Bladder Neoplasms are some of the diseases may be linked to Mouse Anti Human Dickkopf-Related Protein 3.