anti-DLK1 antibody product blog
Tags: Antibody; Monoclonal Antibody; DLK1; anti-DLK1 antibody;
The DLK1 dlk1 (Catalog #MBS476225) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-DLK1 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s DLK1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the DLK1 dlk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The DLK1 dlk1 product has the following accession number(s) (GI #193735077) (NCBI Accession #ACF20049.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-DLK1 Mouse mAb with the following immunoassay(s):
Western Blot (WB) (Western blot analysis using DLK1 mAb against human DLK1 (AA)
Immunofluorescence (IF) (Immunofluorescence analysis of U251 cells using DLK1 mouse mAb (green). Blue)
Flow Cytometry (FC/FACS) (Flow cytometric analysis of NIH/3T3 cells using DLK1 mouse mAb (green) and negative control (red).)
Entrez Summary: This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.
Immunogen: Purified recombinant fragment of human DLK1 expressed in E Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DLK1 are readily searchable from our website. Different antibodies against the same target such as DLK1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Carcinoma, Hepatocellular, Congenital Abnormalities, Disease Models, Animal, Hypertrophy, Inflammation, Insulin Resistance, Liver Diseases, Liver Neoplasms, Necrosis, Nervous System Diseases are some of the diseases may be linked to Anti-DLK1 Mouse mAb.