anti-DTX3L antibody product blog
Tags: Antibody; Monoclonal Antibody; DTX3L; anti-DTX3L antibody;
The DTX3L n/a (Catalog #MBS6006470) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The DTX3L (E3 Ubiquitin-protein Ligase DTX3L, B-lymphoma- and BAL-associated Protein, Protein Deltex-3-like, Rhysin-2, Rhysin2, BBAP) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s DTX3L can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC).Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 6ug/ml. Researchers should empirically determine the suitability of the DTX3L n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below:
SHLRPPSPLL VRVYKSGPRV RRKLESYFQS SKSSGGGECT VSTQEHEAPG TFRVEFSERA AKERVLKKGE HQILVDEKPV PIFLVPTENS IKKNTRPQIS SLTQSQAE.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the DTX3L (E3 Ubiquitin-protein Ligase DTX3L, B-lymphoma- and BAL-associated Protein, Protein Deltex-3-like, Rhysin-2, Rhysin2, BBAP) with the following immunoassay(s):
Western Blot (WB) (Western Blot detection against Immunogen (37.99kD).)
Western Blot (WB) (DTX3L monoclonal antibody, Western Blot analysis of DTX3L expression in A-431.)
Immunohistochemistry (IHC) (Immunoperoxidase of monoclonal antibody to DTX3L on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 6ug/ml].)
Testing Data (Detection limit for recombinant GST tagged DTX3L is ~0.3ng/ml as a capture antibody.)
Ubiquitin ligase that mediates monoubiquitination of \'Lys-91\' of histone H4 (H4K91ub1), in response to DNA damage. Protects cells exposed to DNA-damaging agents. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 \'Lys-20\' methylation (H4K20me). Involved in the recruitment of 53BP1/TP53BP1 to sites of DNA damage by mediating H4K91ub1 formation.
Immunogen: Partial recombinant protein corresponding to aa3-111 from human DTX3L (NP_612144) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DTX3L are readily searchable from our website. Different antibodies against the same target such as DTX3L may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.