anti-EGF antibody product blog
Tags: Antibody; EGF; Monoclonal Antibody; anti-EGF antibody;
The EGF epidermal growth factor/ egf (Catalog #MBS592025) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The mAb anti-Human EGF reacts with Human. Other species not testedDoes not cross react with other human cytokines tested such as IL-1beta, IL-8, MCAF, TGF-beta and SAA. and may cross-react with other species as described in the data sheet. MyBioSource\'s EGF can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA).
ELISA: The antibody can be used in sandwich ELISA for EGF detection. The matched antibody (capture) is clone S-134.
Western blot: The antibody recognized recombinant EGF on western blot. Researchers should empirically determine the suitability of the EGF epidermal growth factor/ egf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The EGF epidermal growth factor/ egf product has the following accession number(s) (GI #688072) (NCBI Accession #AAB32226.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the mAb anti-Human EGF with the following immunoassay(s):
Western Blot
Imunocytochemistry
Epidermal growth factor (EGF), along with its receptor EGFR, plays an important role in cell proliferation, differentiation and survival. The binding of EGF to EGFR triggers the intrinsic tyrosine kinase activity of EGFR, activates signalling molecules and stimulates the synthesis of proteins and DNAs.
EGF is crucial for maintaining mucosal lining in gastrointestinal duct and for healing of oral and gastroesophageal ulcers. EGF signalling is needed for cancer growth. Monoclonal antibodies that block EGFR have been applied for lung cancer and colon cancer treatment.
Target Protein: Human EGF
Immunogen: Purified recombinant human EGF, 6kDa, 53 amino acid residues
Myeloma: Sp2/0-Ag14
Light Chain: Kappa
Reconstitution: Double distilled water is recommended to reconstitute the antibody. Research Area: Growth Factor and Cytokine. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing EGF are readily searchable from our website. Different antibodies against the same target such as EGF may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.