anti-EPHB4� antibody product blog
Tags: Antibody; Monoclonal Antibody; EPHB4; anti-EphB4� antibody;
The EPHB4� ephb4 (Catalog #MBS2543892) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human�EPHB4� Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s EPHB4� can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA).ELISA: 0.1-0.2 mug/mL. This antibody can be used at 0.1-0.2 mug/mL with the appropriate secondary reagents to detect Human EphB4/Eph Receptor B4. Researchers should empirically determine the suitability of the EPHB4� ephb4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The EPHB4� ephb4 product has the following accession number(s) (GI #32528301). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephrin and Eph family are local mediators of cell function through largely contact-dependent processes in development and in maturity. Furthermore, EphB4 protein and the corresponding ligand Ephrin-B2 contribute to tumor growth in various human tumors. EphB4 protein has tumor suppressor activities and that regulation of cell proliferation, extracellular matrix remodeling, and invasive potential are important mechanisms of tumor suppression. Therefore, Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers.
Immunogen: Recombinant Human EphB4/Eph Receptor B4 Protein
Buffer: 0.2 mum filtered solution in PBS. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing EPHB4� are readily searchable from our website. Different antibodies against the same target such as EPHB4� may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Breast Neoplasms, Carcinoma, Hepatocellular, Hyperplasia, Inflammation, Lung Diseases, Lung Neoplasms, Neoplasm Invasiveness, Neoplasm Metastasis, Neoplasms, Experimental, Ovarian Neoplasms are some of the diseases may be linked to Rabbit anti Human�EPHB4� Monoclonal Antibody. The following patways have been known to be associated with this gene. EPHB4� also interacts with the following gene(s): EFNA1, EFNA2, EFNA5, EFNB1, EFNB2, EFNB3, PIK3CA, PTEN, RAC1, VEGFA. Bone, Brain, Embryonic Tissue, Eye, Heart, Liver, Lung, Muscle, Prostate, Vascular tissues are correlated with this protein.