anti-ERBB2 antibody product blog
Tags: Antibody; Monoclonal Antibody; ERBB2; anti-ERBB2 antibody; HER2;
The ERBB2 erbb2 (Catalog #MBS8241405) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-HER2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s HER2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Western Blot: (1/2000 - 1/5000); Immunohistochemistry: (1/100 - 1/200). Researchers should empirically determine the suitability of the ERBB2 erbb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ERBB2 erbb2 product has the following accession number(s) (GI #119533) (NCBI Accession #P04626.1) (Uniprot Accession #P04626). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-HER2 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of HER2 expression in Hela (A), mouse brain (B) whole cell lysates.)
Immunohistochemistry (IHC) (Immunohistochemical analysis of HER2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Mouse monoclonal to HER2.
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence of human HER2. The exact sequence is proprietary. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ERBB2 are readily searchable from our website. Different antibodies against the same target such as ERBB2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adenocarcinoma, Breast Neoplasms, Carcinogenesis, Disease Progression, Gastrointestinal Neoplasms, Lung Neoplasms, Lymphatic Metastasis, Neoplasm Metastasis, Neoplasms, Experimental, Recurrence are some of the diseases may be linked to Anti-HER2 Antibody. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Heart, Liver, Lung, Lymph Node, Mammary Gland, Prostate, Stomach tissues are correlated with this protein. ERBB2 also interacts with the following gene(s): CTNNB1, EGFR, ERBB2IP, ERBB3, GRB2, HSP90AA1, PTPN11, SHC1, SRC, UBC.