anti-ERCC4 antibody product blog
Tags: Antibody; Monoclonal Antibody; ERCC4; anti-ERCC4 antibody;
The ERCC4 ercc4 (Catalog #MBS831628) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s ERCC4 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB).FC: 1:100
IF: 1:100
WB: 1:200-500. Researchers should empirically determine the suitability of the ERCC4 ercc4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ERCC4 ercc4 product has the following accession number(s) (GI #4885217) (NCBI Accession #NP_005227) (Uniprot Accession #Q92889). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ERCC4 antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant ERCC4 protein (Right) or empty vector (Left) detected with ERCC4 antibody)
Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant ERCC4 protein using ERCC4 antibody)
Mouse monoclonal ERCC4 antibody.
Biological Significance: The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5\' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Cross-Reactivity: Human, Dog, Rat, Monkey, Mouse
Immunogen: ERCC4 antibody was raised in mouse using a full length recombinant protein of human ERCC4 (NP_005227) produced in HEK293 cell as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ERCC4 are readily searchable from our website. Different antibodies against the same target such as ERCC4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bone, Brain, Eye, Liver, Lung, Lymph Node, Mammary Gland, Ovary, Prostate, Thymus tissues are correlated with this protein. ERCC4 also interacts with the following gene(s): ERCC1, ERCC2, ERCC5, MSH2, POLD1, RAD52, SLX4, XPA, XPC. Anemia, Breast Neoplasms, Chromosome Aberrations, Genetic Predisposition to Disease, Lung Diseases, Lung Neoplasms, Neoplasms, Experimental, Neoplasms, Germ Cell and Embryonal, Nervous System Diseases, Precancerous Conditions are some of the diseases may be linked to ERCC4 antibody. The following patways have been known to be associated with this gene.