|The ESAM esam (Catalog #MBS6007556) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ESAM (Endothelial Cell-selective Adhesion Molecule, UNQ220/PRO246, W117m) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ESAM can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA).
Suitable for use in ELISA. Researchers should empirically determine the suitability of the ESAM esam for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ESAM esam product has the following accession number(s) (GI #148664205) (NCBI Accession #NP_620411.2) (Uniprot Accession #Q96AP7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MISLPGPLVT NLLRFLFLGL SALAPPSRAQ LQLHLPANRL QAVEGGEVVL PAWYTLHGEV SSSQPWEVPF VMWFFKQKEK EDQVLSYING VTTSKPGVSL VYSMPSRNLS LRLEGLQEKD SGPYSCSVNV QDKQGKSRGH SIKTLELNVL VPPAPPSCRL QGVPHVGANV TLSCQSPRSK PAVQYQWDRQ LPSFQTFFAP ALDVIRGSLS LTNLSSSMAG VYVCKAHNEV GTAQCNVTLE VSTGPGAAVV AGAVVGTLVG LGLLAGLVLL YHRRGKALEE PANDIKEDAI APRTLPWPKS SDTISKNGTL SSVTSARALR PPHGPPRPGA LTPTPSLSSQ ALPSPRLPTT DGAHPQPISP IPGGVSSSGL SRMGAVPVMV PAQSQAGSLV.
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Can mediate aggregation most likely through a homophilic molecular interaction.
Immunogen: Full length recombinant protein corresponding to aa1-391 from human ESAM (AAH16868) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ESAM are readily searchable from our website. Different antibodies against the same target such as ESAM may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. ESAM also interacts with the following gene(s): ANGPT2, CLDN5, VWF. Blood, Bone, Brain, Kidney, Liver, Lung, Lymph Node, Muscle, Ovary, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene. Arteriosclerosis, Carcinoma, Inflammation, Kidney Diseases, Liver Diseases, Lung Neoplasms, Neoplasms, Neoplasms, Experimental, Nervous System Diseases, Proteinuria are some of the diseases may be linked to ESAM (Endothelial Cell-selective Adhesion Molecule, UNQ220/PRO246, W117m).