anti-ESR1 antibody product blog
Tags: Antibody; Monoclonal Antibody; ESR1; anti-ESR1 antibody; ESR1/ER;
The ESR1 esr1 (Catalog #MBS6008756) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ESR1/ER (ESR1, ESR, NR3A1, Estrogen receptor, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ESR1/ER can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in Western Blot, ELISA.
Dilution: ELISA: 1:1,000
Western Blot: 1:500~3200. Researchers should empirically determine the suitability of the ESR1 esr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ESR1 esr1 product has the following accession number(s) (GI #47824866) (NCBI Accession #NP_001001443.1) (Uniprot Accession #P49884). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ESR1/ER (ESR1, ESR, NR3A1, Estrogen receptor, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1) with the following immunoassay(s):
Western Blot (WB) (ESR1/ER Antibody western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the ESR1/ER antibody detected the ESR1/ER protein (arrow).)
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5\' UTRs and use different promoters.
Immunogen: Purified His-tagged ESR1/ER protein (fragment). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ESR1 are readily searchable from our website. Different antibodies against the same target such as ESR1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.