|The FAIM3 faim3 (Catalog #MBS644820) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The FAIM3 (Fas Apoptotic Inhibitory Molecule 3, Regulator of Fas-induced Apoptosis Toso, TOSO) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s FAIM3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the FAIM3 faim3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FAIM3 faim3 product has the following accession number(s) (GI #301069341) (NCBI Accession #NP_001180267.1) (Uniprot Accession #O60667). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
SEYEPSWEEQ PMPETPKWFH LPYLFQMPAY ASSSKFVTRV TTPAQRGKVP PVHHSSPTTQ ITHRPRVSRA SSVAGDKPRT FLPSTTASKI SALEGLLKPQ.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Immunogen: Partial recombinant corresponding to aa124-223 from FAIM3 (AAH06401) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FAIM3 are readily searchable from our website. Different antibodies against the same target such as FAIM3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Heart, Lung, Placenta, Spleen tissues are correlated with this protein. FAIM3 also interacts with the following gene(s): CD19. Necrosis, Neoplasms are some of the diseases may be linked to FAIM3 (Fas Apoptotic Inhibitory Molecule 3, Regulator of Fas-induced Apoptosis Toso, TOSO).