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anti-FGFR2 antibody product blog

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Posted on 2015-08-21 09:24:41 by mybiosource_staff
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Tags: Antibody; Monoclonal Antibody; FGFR2; anti-FGFR2 antibody;
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The FGFR2 fgfr2 (Catalog #MBS831645) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The FGFR2 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s FGFR2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 1:2000. Researchers should empirically determine the suitability of the FGFR2 fgfr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The FGFR2 fgfr2 product has the following accession number(s) (GI #221316639) (NCBI Accession #NP_000132) (Uniprot Accession #P21802). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the FGFR2 antibody with the following immunoassay(s):
Western Blot (Western Blot analysis using FGFR2 antibody
Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant FGFR2 protein (Right) or empty vector (Left) detected with FGFR2 antibody)
Western Blot FGFR2.

Mouse monoclonal FGFR2 antibody.

Biological Significance: FGFR2 is a member of the fibroblast growth factor receptor family, where amino acid sequenceis highly conserved between members and throughout evolution. FGFR family members differ from one another in theirligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Immunogen: FGFR2 antibody was raised in mouse using a full length recombinant protein of human FGFR2 (NP_000132) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FGFR2 are readily searchable from our website. Different antibodies against the same target such as FGFR2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bone, Brain, Embryonic Tissue, Eye, Lung, Muscle, Prostate, Skin, Stomach, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene. Abnormalities, Multiple, Acrocephalosyndactylia, Breast Neoplasms, Craniofacial Abnormalities, Craniofacial Dysostosis, Craniosynostoses, Limb Deformities, Congenital, Pfeiffer type acrocephalosyndactyly, Skin Diseases, Stomach Neoplasms are some of the diseases may be linked to FGFR2 antibody.
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