anti-FGR antibody product blog
Tags: Antibody; Monoclonal Antibody; FGR; anti-FGR antibody;
The FGR fgr (Catalog #MBS245992) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 6G2] (IgG1) to Human FGR reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s FGR can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA).ELISA (1:10000), IHC-P (1:200), WB (1:500 - 1:2000). Researchers should empirically determine the suitability of the FGR fgr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FGR fgr product has the following accession number(s) (GI #4885235) (NCBI Accession #NP_005239.1) (Uniprot Accession #P09769). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Mouse Monoclonal [clone 6G2] (IgG1) to Human FGR with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-FGR antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.)
Immunohistochemistry (IHC) (Anti-FGR antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.)
Western Blot (WB) (Western blot of anti-FGR mAb against HL60 (1) Raw264.7 (2) cell lysate.)
Protein tyrosine kinase FGR is a non-receptor kinase belonging to the Src subfamily. FGR is associated with cell migration and adhesion, and is a negative regulator of integrin mediated signal transduction. A deficiency in FGR results in defective eosinophil recruitment which is correlated with allergic inflammation.
Target Species: Human
Immunogen Description: Purified recombinant fragment of human FGR expressed in E Coli. Immunogen: FGR antibody was raised against purified recombinant fragment of human FGR expressed in E Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FGR are readily searchable from our website. Different antibodies against the same target such as FGR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Bone Marrow, Brain, Embryonic Tissue, Heart, Liver, Placenta, Uterus, Vascular tissues are correlated with this protein. Carcinoma, Cardiovascular Diseases, Congenital Abnormalities, Fetal Death, Inflammation, Lung Diseases, Necrosis, Neoplasms, Experimental, Premature Birth, Weight Gain are some of the diseases may be linked to Mouse Monoclonal [clone 6G2] (IgG1) to Human FGR.