anti-FH antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-FH antibody; FH/Fumarase;
The FH n/a (Catalog #MBS8505095) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The FH/Fumarase Mouse Monoclonal Antibody (2B11) reacts with Human, Rat, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s FH/Fumarase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).WB: 1:1,000-3,000. Researchers should empirically determine the suitability of the FH n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the FH/Fumarase Mouse Monoclonal Antibody (2B11) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of 1) Hela, 2)Mouse Brain Tissue, 3) Rat Brain tissue with E12-196 diluted at 1:2, 000.)
Fumarase (FH) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle), and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate. Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form, while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety.
In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FH are readily searchable from our website. Different antibodies against the same target such as FH may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.