|The FIP1L1 fip1l1 (Catalog #MBS642048) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The FIP1L1 (Rearranged in Hypereosinophilia, FIP1-like 1 Protein, Factor Interacting with PAP, Pre-mRNA 3\'-end-processing Factor FIP1, hFip1, FIP1, RHE, DKFZp586K0717, FLJ33619) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s FIP1L1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the FIP1L1 fip1l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FIP1L1 fip1l1 product has the following accession number(s) (GI #71297101) (NCBI Accession #AAH52959.1) (Uniprot Accession #Q6UN15). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MSAGEVERLV SELSGGTGGD EEEEWLYGDE NEVERPEEEN ASANPPSGIE DETAENGVPK PKVTETEDDS DSDSDDDEDD VHVTIGDIKT GAPQYGSYGT APVNLNIKTG GRVYGTTGTK VKGVDLDAPG SINGVPLLEV DLDSFEDKPW RKPGADLSDY FNYGFNEDTW KAYCEKQKRI RMGLEVIPVT STTNKITAED CTMEVTPGAE IQDGRFNLFK VQQGRTGNSE KETALPSTKA EFTSPPSLFK TGLPPSRNST SSQSQTSTAS RKANSSVGKW QDRYGRAESP DLRRLPGAID VIGQTITISR VEGRRRANEN SNIQVLSERS ATEVDNNFSK PPPFFPPGAP PTHLPPPPFL PPPPTVSTAP PLIPPPGK.
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Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3\'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex.
Immunogen: Full length recombinant corresponding to aa1-379 from human FIP1L1 (AAH17724) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FIP1L1 are readily searchable from our website. Different antibodies against the same target such as FIP1L1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. FIP1L1 also interacts with the following gene(s): CHIC2, KIT, PDGFRA, PDGFRB.