anti-FLT1� antibody product blog
Tags: Antibody; Monoclonal Antibody; FLT1�; anti-FLT1� antibody;
The FLT1� flt1 (Catalog #MBS2543854) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human�FLT1� Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s FLT1� can be used in a range of immunoassay formats including, but not limited to, Flow Cyometry (FC/FACS).Flow Cytometry: 0.5-2 mug/Test. Researchers should empirically determine the suitability of the FLT1� flt1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FLT1� flt1 product has the following accession number(s) (GI #24660372). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to the�protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1/FLT1 contains seven�Ig-like C2-type (immunoglobulin-like) domains and one�protein kinase domain. VEGFR-1/FLT1 is expressed mostly in normal lung, but also in placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. VEGFR-1/FLT1 is not expressed in tumor cell lines. VEGFR-1/FLT1 is an essential receptor tyrosine kinase that regulates mammalian vascular development and embryogenesis. EGF-induced angiogenesis requires inverse regulation of VEGFR-1 and VEGFR-2 in tumor-associated endothelial cells. VEGFR-1/FLT1 is a receptor for VEGF, VEGFB and PGF. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.
Immunogen: Recombinant Human VEGFR1/FLT-1 protein
Buffer: 0.2 mum filtered solution in PBS with 5% trehalose. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FLT1� are readily searchable from our website. Different antibodies against the same target such as FLT1� may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. FLT1� also interacts with the following gene(s): EPAS1, HIF1A, NRP1, NRP2, PGF, SHC1, VEGFA, VEGFB. Blood, Bone, Embryonic Tissue, Heart, Kidney, Liver, Lung, Muscle, Placenta, Vascular tissues are correlated with this protein.