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anti-FOXO1 antibody product blog

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Posted on 2015-08-19 17:30:57 by mybiosource_staff
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Tags: Antibody; FOXO1; Monoclonal Antibody; anti-FOXO1 antibody;
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The FOXO1 foxo1 (Catalog #MBS857730) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The FOXO1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s FOXO1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the FOXO1 foxo1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The FOXO1 foxo1 product has the following accession number(s) (GI #9257222) (NCBI Accession #NP_002006.2) (Uniprot Accession #Q12778). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the FOXO1 Antibody with the following immunoassay(s):
Testing Data (Western blot detection of FOXO1(C-terminus) antibody in A431&Hela cell lysates using FOXO1(C-terminus) antibody (1:1000 diluted). Predicted band size:70KDa Observed band size: 70KDa.)
Testing Data FOXO1.

UniPort Summary Function: Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence (By similarity)
Entrez Summary: This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.

Immunogen: Purified recombinant human FOXO1(C-terminus) protein fragments expressed in E Coli.
Cellular Localization: Cytoplasm; Nucleus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FOXO1 are readily searchable from our website. Different antibodies against the same target such as FOXO1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Atrophy, Cardiovascular Diseases, Fatty Liver, Hyperglycemia, Inflammation, Insulin Resistance, Liver Diseases, Necrosis, Neoplasms, Rhabdomyosarcoma, Alveolar are some of the diseases may be linked to FOXO1 Antibody. FOXO1 also interacts with the following gene(s): AKT1, CDKN1A, CTNNB1, DYRK1A, FOXG1, HNF4A, PPARG, SIRT1, SMAD3, SRC. The following patways have been known to be associated with this gene.
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