anti-FSTL1� antibody product blog
Tags: Antibody; Monoclonal Antibody; FSTL1�; anti-FSTL1� antibody;
The FSTL1� fstl1 (Catalog #MBS2544114) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human�FSTL1� Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s FSTL1� can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cyometry (FC/FACS).Flow Cytometry: 0.5-2 mug/Test
ICC/IF: 10-25 mug/mL. Researchers should empirically determine the suitability of the FSTL1� fstl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FSTL1� fstl1 product has the following accession number(s) (GI #5901956). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Follistatin-related protein 1 (FSTL1)� is an extracellular glycoprotein whose functional significance in physiological and pathological processes is incompletely understood. Recently, we have shown that FSTL1 acts as a muscle-derived secreted factor that is up-regulated by Akt activation and ischemic stress and that FSTL1 exerts favorable actions on the heart and vasculature. Here, we sought to identify the receptor that mediates the cellular actions of FSTL1. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. FSTL1 is thought to be an autoantigen associated with rheumatoid arthritis. DIP2A functions as a novel receptor that mediates the cardiovascular protective effects of FSTL1. Experiment results have provided in vivo and in vitro evidence to demonstrate that Fstl1 modulates lung development and alveolar maturation, in part, through BMP4 signaling.
Immunogen: Recombinant Human FSTL1 protein
Buffer: 0.2 mum filtered solution in PBS. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FSTL1� are readily searchable from our website. Different antibodies against the same target such as FSTL1� may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. FSTL1� also interacts with the following gene(s): BMP2, BMP4, CD14, CD86, MYOD1. Carcinoma, Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Heart Diseases, Hypertrophy, Inflammation, Kidney Diseases, Myocardial Infarction, Necrosis are some of the diseases may be linked to Rabbit anti Human�FSTL1� Monoclonal Antibody. The following patways have been known to be associated with this gene. Bone, Bone Marrow, Brain, Connective Tissue, Embryonic Tissue, Heart, Kidney, Lung, Muscle, Vascular tissues are correlated with this protein.