anti-FTL antibody product blog
Tags: Antibody; Monoclonal Antibody; Ferritin Light Chain; FTL; anti-FTL antibody;
The FTL ftl (Catalog #MBS832660) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Ferritin Light Chain can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).WB: 1:5000. Researchers should empirically determine the suitability of the FTL ftl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FTL ftl product has the following accession number(s) (GI #20149498) (NCBI Accession #NP_000137.2) (Uniprot Accession #P02792). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Ferritin Light Chain antibody with the following immunoassay(s):
Western Blot (WB) ()
Mouse monoclonal Ferritin Light Chain antibody.
Immunogen: Recombinant human protein purified from E.coli (His-FL)
Cross-Reactivity: Human
Biological Significance: Ferritin is an ubiquitous and highly conserved protein which plays a major role in iron homeostasis. It is a holoenzyme shell (~450 kDa) consisting of 24 subunits of two types, H (heavy) and L (light), and capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiologic status of the cell, the ratio of H to L subunits in ferritin can vary widely. It can be viewed not only as part of a group of iron regulatory proteins that include transferrin and the transferrin receptor, but also as a member of the protein family that orchestrates the cellular defense against stress and inflammation. Ferritin is found in the liver, spleen, kidney and heart. Only a small amount is found in the blood. The blood level of ferritin serves as an indicator of the amount of iron stored in the body. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FTL are readily searchable from our website. Different antibodies against the same target such as FTL may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Brain, Eye, Heart, Liver, Lung, Muscle, Nerve, Spleen, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene. Brain Diseases, Breast Neoplasms, Cardiovascular Diseases, Cognition Disorders, Heredodegenerative Disorders, Nervous System, Hyperferritinemia, hereditary, with congenital cataracts, Inflammation, Iron Metabolism Disorders, Nervous System Diseases, Neuroferritinopathy are some of the diseases may be linked to Ferritin Light Chain antibody.