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anti-FYN antibody product blog

Posted on 2015-11-10 08:19:56 by mybiosource_staff
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Tags: Antibody; anti-Fyn antibody; Fyn; Monoclonal Antibody;
The FYN fyn (Catalog #MBS850994) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The FYN Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s FYN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS), ELISA (EIA).
WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF: 1/200-1/1000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000
Not yet tested in other applications. Researchers should empirically determine the suitability of the FYN fyn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The FYN fyn product has the following accession number(s) (GI #4503823) (NCBI Accession #NP_002028.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the FYN Antibody with the following immunoassay(s):
Testing Data (Figure 1: Western blot analysis using FYN mouse mAb against Hela cell lysate.)
Testing Data FYN.

Testing Data #2 (Figure 2: Immunohistochemical analysis of paraffin-embedded breast cancer tissues (left) and brain tissues (right) using FYN mouse mAb with DAB staining.)
Testing Data #2 FYN.

Testing Data #3
Testing Data #3 FYN.

Background: This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.

Immunogen: Purified recombinant fragment of human FYN expressed in E. Coli.
Species: Mouse IgG1. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FYN are readily searchable from our website. Different antibodies against the same target such as FYN may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Kidney, Lung, Muscle, Nerve, Spleen, Thymus, Vascular tissues are correlated with this protein. Brain Diseases, Breast Neoplasms, Cell Transformation, Neoplastic, Heart Diseases, Inflammation, Kidney Diseases, Lung Diseases, Necrosis, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to FYN Antibody. FYN also interacts with the following gene(s): BCAR1, CBL, FYB, GP6, GRIN2B, KHDRBS1, SH2D1A.
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