|The GCG gcg (Catalog #MBS602182) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Glucagon-like Peptide 1 (1-36) amide (human) (GLP1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Glucagon-like Peptide 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA).
Suitable for use in ELISA.
Dilution: ELISA: 1:20,000 (1). Researchers should empirically determine the suitability of the GCG gcg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GCG gcg product has the following accession number(s) (GI #4503945) (NCBI Accession #NP_002045.1) (Uniprot Accession #P01275). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. GLP-1 (1-36) amide is an incompletely prosessed precursor form showing relatively little bioactivity.
Immunogen: Synthetic peptide.
Culture Medium: RPMI 1640 with 10% fetal calf serum. Hybridoma: X63-Ag8.653. Female CF1 x Balb c mice immunized i.p. with immunogen adsorbed onto Al(OH)3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GCG are readily searchable from our website. Different antibodies against the same target such as GCG may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. GCG also interacts with the following gene(s): FOXA2, GCGR, GIPR, GLP1R, GLP2R, SCT. The following patways have been known to be associated with this gene. Intestine, Pancreas tissues are correlated with this protein. Diabetes Mellitus, Heart Diseases, Hyperglycemia, Hyperinsulinism, Insulin Resistance, Kidney Diseases, Liver Diseases, Muscular Diseases, Obesity, Vascular Diseases are some of the diseases may be linked to Glucagon-like Peptide 1 (1-36) amide (human) (GLP1).