anti-GLUT1 antibody product blog
Tags: Antibody; Monoclonal Antibody; GLUT1; anti-GLUT1 antibody;
The GLUT-1 slc2a1 (Catalog #MBS2540197) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The GLUT-1 Monoclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s GLUT-1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA).WB: 1:500-1:3000
IHC: 1:20-1:800. Researchers should empirically determine the suitability of the GLUT-1 slc2a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GLUT-1 slc2a1 product has the following accession number(s) (GI #166795299) (NCBI Accession #NP_006507.2) (Uniprot Accession #P11166). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GLUT-1 Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HEK-293 cells using GLUT1 Monoclonal Antibody at dilution of 1:1500)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin embedded human lung cancer tissue slide using GLUT1 Monoclonal Antibody at dilution of 1:300)
GLUT1, also known as SLC2A1, is an ubiquitously expressed glucose transporter and responsible for the basal level of glucose uptake in most cell types. Human erythrocytes express the highest level of the GLUT1. Defects in SLC2A1 are the cause of GLUT1 deficiency syndrome type 1 and type 2. High expression of GLUT1 has been reported to be a reliable immunohistochemical marker for juvenile hemangiomas. GLUT1 protein may appear as two or more distinct forms among 43 kDa to 55 kDa due to the different glycosylation state. And the conversion of highly glycosylated form of GLUT1 to less glycosylated form has been reported to correlate to differentiation. (8263524, 23302780).
Immunogen: Fusion protein of GLUT1. Note: Centrifuge before opening to ensure complete recovery of vial contents. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GLUT-1 are readily searchable from our website. Different antibodies against the same target such as GLUT-1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. GLUT-1 also interacts with the following gene(s): GAPDH, GIPC1, PTK2B, STOM. The following patways have been known to be associated with this gene. Adenocarcinoma, Brain Diseases, Breast Neoplasms, Cardiovascular Diseases, Diabetes Mellitus, Type 2, Kidney Diseases, Liver Diseases, Necrosis, Neoplasms, Seizures are some of the diseases may be linked to GLUT-1 Monoclonal Antibody.