anti-GPHN antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-GPHN antibody; GPHN;
The GPHN gphn (Catalog #MBS830899) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s GPHN can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB).FC: 1:100
IF: 1:100
WB: 1:2000. Researchers should empirically determine the suitability of the GPHN gphn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GPHN gphn product has the following accession number(s) (GI #10880983) (NCBI Accession #NP_065857) (Uniprot Accession #Q9NQX3). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GPHN antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant GPHN protein (Right) or empty vector (Left) detected with GPHN antibody)
Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant GPHN protein using GPHN antibody)
Mouse monoclonal GPHN antibody.
Biological Significance: GPHN is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. Cross-Reactivity: Human
Immunogen: GPHN antibody was raised in mouse using a full length recombinant protein of human GPHN (NP_065857) as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GPHN are readily searchable from our website. Different antibodies against the same target such as GPHN may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. GPHN also interacts with the following gene(s): GABRG2, GLRB, MOCS1, MOCS2. Blood, Bone, Brain, Eye, Kidney, Lung, Muscle, Nerve, Prostate, Spinal Cord tissues are correlated with this protein. The following patways have been known to be associated with this gene. Cell Transformation, Neoplastic, Disease Models, Animal, Drug-Related Side Effects and Adverse Reactions, Immune System Diseases, Lung Neoplasms, Memory Disorders, Molybdenum cofactor deficiency, Neoplasms, Experimental, Neurotoxicity Syndromes, Poisoning are some of the diseases may be linked to GPHN antibody.