anti-GPX3 antibody product blog
Tags: Antibody; GPX3; Monoclonal Antibody; anti-GPX3 antibody; glutathione peroxidase 3;
The GPX3 gpx3 (Catalog #MBS840072) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Glutathione Peroxidase 3 Antibody (Clone 55A) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Glutathione Peroxidase 3 can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP), ELISA (EIA), Western Blot (WB).IP: 1-2 ul, ELISA. Researchers should empirically determine the suitability of the GPX3 gpx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GPX3 gpx3 product has the following accession number(s) (GI #6006001) (NCBI Accession #NP_002075.2) (Uniprot Accession #P22352). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Glutathione Peroxidase 3 Antibody (Clone 55A) with the following immunoassay(s):
Testing Data
Monoclonal antibody to detect Glutathione Peroxidase 3 in human samples.
Background: Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic /mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.
Immunogen: Recombinant human protein purified from E.coli
Positive Control: WB and IP:Bosc23 cell lysate. Handling: The antibody solution should be gently mixed before use. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GPX3 are readily searchable from our website. Different antibodies against the same target such as GPX3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.