anti-Grin1 antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-GRIN1 antibody; GRIN1; GluN1-NR1;
The Grin1 grin1 (Catalog #MBS803986) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The GluN1-NR1 Antibody: PerCP reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s GluN1-NR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC).1ug/mL (WB), 0.1-1ug/mL (IHC). Researchers should empirically determine the suitability of the Grin1 grin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Grin1 grin1 product has the following accession number(s) (GI #8393484) (NCBI Accession #NP_058706.1) (Uniprot Accession #P35439). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GluN1-NR1 Antibody: PerCP with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Rat brain membrane lysate showing detection of NMDAR1 NMDA receptor protein using Mouse Anti-NMDAR1 NMDA receptor Monoclonal Antibody, Clone S308-48. Primary Antibody: Mouse Anti-NMDAR1 NMDA receptor Monoclonal Antibody at 1:1000.)
Background Info: Detects ~105kDa
Scientific Background: The NMDA receptor (NMDAR), a glutamate receptor, is the predominant molecular device for controlling synaptic plasticity and memory function (1). The NMDA receptor forms a heterotetramer between two NR1 and two NR2 subunits (the subunits are also called glutamate-binding NMDA receptor subunits or GluN for short); two obligatory NR1 subunits and two regionally localized NR2 subunits. A related gene family of NR3 An and B subunits have an inhibitory effect on receptor activity. Multiple receptor isoforms with distinct brain distributions and functional properties arise by selective splicing of the NR1 transcripts and differential expression of the NR2 subunits.
Conjugate: PerCP. Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Grin1 are readily searchable from our website. Different antibodies against the same target such as Grin1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Eye tissues are correlated with this protein. Brain Diseases, Disease Models, Animal, Learning Disorders, Memory Disorders, Movement Disorders, Nerve Degeneration, Nervous System Diseases, Pain, Poisoning, Seizures are some of the diseases may be linked to GluN1-NR1 Antibody: PerCP.