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anti-Grm5 antibody product blog

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Posted on 2015-10-26 20:22:20 by mybiosource_staff
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Tags: Antibody; Monoclonal Antibody; anti-GRM5 antibody; GRM5; mGluR1/5;
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The Grm5 grm5 (Catalog #MBS800532) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The mGluR1/5 Antibody: ATTO 390 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s mGluR1/5 can be used in a range of immunoassay formats including, but not limited to, Western (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP).
1ug/mL (WB), 0.1-1ug/mL (IHC). Researchers should empirically determine the suitability of the Grm5 grm5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The Grm5 grm5 product has the following accession number(s) (GI #8393490) (NCBI Accession #NP_058708.1) (Uniprot Accession #P31424). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the mGluR1/5 Antibody: ATTO 390 with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Rat brain membrane lysate showing detection of mGluR5 Glutamate Receptor protein using Mouse Anti-mGluR5 Glutamate Receptor Monoclonal Antibody, Clone S75-33 (SMC-407). Primary Antibody: Mouse Anti-mGluR5 Glutamate Receptor Monoclonal Antibody (SMC-407) at 1:1000.)
Western Blot (WB) Grm5.

Background Info: Detects ~130kDa (both mGluR1 and mGluR5)

Scientific Background: The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers (3, 4).

Conjugate: ATTO 390. Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Grm5 are readily searchable from our website. Different antibodies against the same target such as Grm5 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Brain tissues are correlated with this protein. Brain Diseases, Central Nervous System Diseases, Disease Models, Animal, Mental Disorders, Movement Disorders, Nervous System Diseases, Neurobehavioral Manifestations, Pain, Seizures, Substance-Related Disorders are some of the diseases may be linked to mGluR1/5 Antibody: ATTO 390.
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