anti-GRM7 antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-GRM7 antibody; GRM7; mGluR7;
The GRM7 grm7 (Catalog #MBS600401) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The mGluR7 (G Protein-coupled Metabotropic Glutamate Receptor, GRM7, FLJ40498, GLUR7, GPRC1G, mGlu7) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s mGluR7 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS).Suitable for use in Flow cytometry.,, Recommended Dilutions:, Flow cytometry: 25ug/ml and add 10 il of the diluted solution to 1-2.5 x 10e5 cells in a, total reaction volume not exceeding 200ul., Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the GRM7 grm7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GRM7 grm7 product has the following accession number(s) (GI #32528268) (NCBI Accession #NP_870989.1) (Uniprot Accession #Q14831). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. Metabotropic glutamate receptor 7 (mGLUR7), also called GRM7 (G protein-coupled.
Immunogen: HEK293 cells transfected with rhMGLUR7. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GRM7 are readily searchable from our website. Different antibodies against the same target such as GRM7 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. GRM7 also interacts with the following gene(s): GRIP1. Breast Neoplasms, Neurodegenerative Diseases, Neurologic Manifestations are some of the diseases may be linked to mGluR7 (G Protein-coupled Metabotropic Glutamate Receptor, GRM7, FLJ40498, GLUR7, GPRC1G, mGlu7).