|The GSTT2 gstt2 (Catalog #MBS830144) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The GSTT2 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s GSTT2 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB).
WB: 1:2000. Researchers should empirically determine the suitability of the GSTT2 gstt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GSTT2 gstt2 product has the following accession number(s) (GI #4504187) (NCBI Accession #NP_000845) (Uniprot Accession #P0CG29). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GSTT2 antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant GSTT2 protein (Right) or empty vector (Left) detected with GSTT2 antibody)
Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant GSTT2 protein using GSTT2 antibody)
Mouse monoclonal GSTT2 antibody.
Biological Significance: Glutathione S-transferase (GSTs) theta 2 (GSTT2) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: Alpha, Mu, Pi, Theta, and Zeta. The theta class members GSTT1 and GSTT2 share 55% amino acid sequence identity and both are thought to have an important role in human carcinogenesis. Immunogen: GSTT2 antibody was raised in mouse using a full length recombinant protein of human GSTT2 (NP_000845) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GSTT2 are readily searchable from our website. Different antibodies against the same target such as GSTT2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. GSTT2 also interacts with the following gene(s): GSTO1, GSTP1, GSTZ1. The following patways have been known to be associated with this gene. Brain, Eye, Heart, Kidney, Liver, Lung, Ovary, Salivary Gland, Skin, Testis tissues are correlated with this protein. Adenocarcinoma, Brain Diseases, Carcinoma, Cardiovascular Diseases, Fatty Liver, Inflammation, Liver Diseases, Lung Neoplasms, Neoplasms, Experimental, Precancerous Conditions are some of the diseases may be linked to GSTT2 antibody.