anti-H4 antibody product blog
Tags: Antibody; Monoclonal Antibody; Histone H4; anti-H4 antibody;
The H4 hist1h4a (Catalog #MBS846017) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Histone H4 Rabbit Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Histone H4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB); Immunocytochemistry (ICC); ELISA (EIA); Multiplex.WB: 0.1 ug/ml- 0.5 ug/ml
ICC: 1 mug/ml- 2 mug/ml
ELISA: 0.2 ug/ml- 1 ug/ml
Multiplex: 0.1 ug/ml- 0.5 ug/ml. Researchers should empirically determine the suitability of the H4 hist1h4a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The H4 hist1h4a product has the following accession number(s) (GI #77539758) (NCBI Accession #NP_001029249.1) (Uniprot Accession #P62805). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Rabbit monoclonal antibody to detect Histone H4 in Human; mouse and rat samples.
The nucleosome is made up of four core histone proteins (H2A; H2B; H3 and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranscriptional modification including acetylation; phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression.
Immunogen: A peptide corresponding to the C-terminus of human Histone H4. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing H4 are readily searchable from our website. Different antibodies against the same target such as H4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.