anti-HCN4 Cyclic nucleotide-gated Channel antibody product blog
Tags: Antibody; Monoclonal Antibody; HCN4 Cyclic nucleotide-gated Channel; anti-HCN4 Cyclic nucleotide-gated Channel antibody;
The HCN4 Cyclic nucleotide-gated Channel n/a (Catalog #MBS190598) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-HCN4 Cyclic Nucleotide-Gated Channel Monoclonal Antibody reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. MyBioSource\'s HCN4 Cyclic nucleotide-gated Channel can be used in a range of immunoassay formats including, but not limited to, Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence.Immunoblotting: use at 1-10ug/ml. A band of ~130kDa is detected. Immunohistochemistry and Immunocytochemistry. use at 0.1-1ug/ml. Immunofluorescence: use at 1-10ug/ml. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: COS cell lysate transiently transfected with HCN4. Researchers should empirically determine the suitability of the HCN4 Cyclic nucleotide-gated Channel n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Hyperpolarization-activated cation channels of the HCN gene family, such as HCN4, play a crucial role in the regulation of cell excitability. They contribute to spontaneous rhythmic activity in the heart and brain.
Antigen: Fusion protein aa 1019-1108 (cytoplasmic C-terminus) of rat HCN4 (accession number Q9JKA7). Dilution Instructions: Dilute in PBS or medium which is identical to that used in the assay system. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HCN4 Cyclic nucleotide-gated Channel are readily searchable from our website. Different antibodies against the same target such as HCN4 Cyclic nucleotide-gated Channel may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.