anti-HLA ABC antibody product blog
Tags: Antibody; Monoclonal Antibody; HLA ABC; anti-HLA ABC antibody;
The HLA ABC n/a (Catalog #MBS211179) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s HLA ABC can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen*.Immunohistology - Frozen: Application Note: The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. MyBioSource recommends the use of acetone fixation for frozen sections. Researchers should empirically determine the suitability of the HLA ABC n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the MOUSE ANTI HUMAN HLA ABC:HRP with the following immunoassay(s):
Testing Data (Staining of peripheral blood lymphocytes with Mouse anti Human HLA-ABC: Low Endotoxin (MBS211267))
Testing Data (Staining of human peripheral blood lymphocytes with Mouse anti Human HLA ABC:FITC (MBS211107))
Testing Data (Staining of human peripheral blood lymphocytes with Mouse anti Human HLA ABC:Alexa Fluor 488 (MBS213169A488))
Testing Data (Staining of human peripheral blood lymphocytes with Mouse anti Human HLA ABC (MBS213169))
Testing Data (Staining of human peripheral blood monocytes with Mouse anti Human HLA ABC:Biotin (MBS210522))
Testing Data (Staining of human peripheral blood lymphocytes with Mouse anti Human HLA ABC:Alexa Fluor 647 (MBS213169A647))
Mouse anti Human HLA ABC antibody, clone W6/32 recognizes an antigenic determinant shared among products of the HLA A, B and C loci. Clone W6/32 recognizes a conformational epitope, reacting with HLA class I alpha3 and alpha2 domains. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C. These proteins are found on the surface of almost all nucleated somatic cells. Mouse anti Human HLA ABC antibody, clone W6/32 is routinely tested in flow cytometry on human peripheral blood lymphocytes.
Perservative Stabilisers: 0.01% Thiomersal
Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant. Immunogen: Purified human tonsil lymphocyte membranes.
Histology Positive Control Tissue: Tonsil
Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1/1-Ag4.1 myeloma cell line.
Buffer Solution: Phosphate buffered saline
Target Species: Human. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HLA ABC are readily searchable from our website. Different antibodies against the same target such as HLA ABC may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.