|The HS6ST1 hs6st1 (Catalog #MBS606459) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The HS6ST1 (Heparan-sulfate 6-O-sulfotransferase 1, DKFZp547H098, FLJ25392, Heparan-sulfate 6-O-sulfotransferase 1, HS6ST, HS6ST-1, MGC116899, MGC116901) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s HS6ST1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunohistochemistry (IHC).
Suitable for use in ELISA and Immunohistochemistry.
Dilution: Immunohistochemistry: 25ug/ml. Detects HS6ST1 in paraffin-embedded normal and cancer human liver tissue sections. Researchers should empirically determine the suitability of the HS6ST1 hs6st1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The HS6ST1 hs6st1 product has the following accession number(s) (GI #148747866) (NCBI Accession #NP_004798.3) (Uniprot Accession #O60243). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Heparan-sulfate 6-O-sulfotransferase 1 (HS6ST1) is one of three enzymes that catalyze sulfation at the 6-O position of N-acetylglucosamine residues in heparan sulfate. Heparan sulfate proteoglycans (HSPGs) interact with a variety of proteins, such as growth factors, protease inhibitors, cytokines, lipoprotein lipase and viral envelope proteins. HSPGs play roles in a wide variety of processes including cell growth, differentiation, and motility, blood coagulation, lipid metabolism, and viral infection. Within the lumenal domain, human and mouse HS6ST1 share 97% aa sequence.
Immunogen: Recombinant protein corresponding to aa38-411 from human HS6ST1, CHO derived (Accession# O60243). Hybridoma: Mouse myeloma cells with B cells from mouse immunized with purified, CHO cell-derived recombinant human HS6ST1. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HS6ST1 are readily searchable from our website. Different antibodies against the same target such as HS6ST1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Brain, Embryonic Tissue, Eye, Kidney, Liver, Lung, Muscle, Nerve, Placenta tissues are correlated with this protein. The following patways have been known to be associated with this gene. Female Urogenital Diseases, Neoplasms, Ovarian Neoplasms are some of the diseases may be linked to HS6ST1 (Heparan-sulfate 6-O-sulfotransferase 1, DKFZp547H098, FLJ25392, Heparan-sulfate 6-O-sulfotransferase 1, HS6ST, HS6ST-1, MGC116899, MGC116901).