|The HSP90AB1 n/a (Catalog #MBS830920) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The HSP90AB1 antibody reacts with Human, Dog, Rat, Monkey and may cross-react with other species as described in the data sheet. MyBioSource\'s HSP90AB1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 1:2000. Researchers should empirically determine the suitability of the HSP90AB1 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the HSP90AB1 antibody with the following immunoassay(s):
Western Blot (Western Blot analysis using HSP90AB1 antibody
Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant HSP90AB1 protein (Right) or empty vector (Left) detected with HSP90AB1 antibody)
Mouse monoclonal HSP90AB1 antibody.
Biological Significance: Hsp90 is a human heat shock protein. In response to adverse change in their environment all organisms increase the expression of a class of proteins referred to as heat shock or stress protein. Hsp90, a highly conserved stress-induced protein, is abundantly expressed in most tissues under non-stress conditions and is required for eukaryotic cell viability. Hsp90 is primarily a cytoplasmic protein and its function remains unknown. It exists in a dimeric form and has been observed to bind to several other cellular proteins such as retro-virus kinases, steroid receptor, heme-regulated protein kinase, actin and tubulin. Immunogen: HSP90AB1 antibody was raised in mouse using a protein expressed in 293T cell transfected with human HSP90AB1 expression vector as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HSP90AB1 are readily searchable from our website. Different antibodies against the same target such as HSP90AB1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.