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anti-HSPBP1 antibody product blog

Posted on 2016-02-17 01:18:31 by mybiosource_staff
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Tags: Antibody; Monoclonal Antibody; HspBP1; anti-HspBP1 antibody;
The HSPBP1 hspbp1 (Catalog #MBS830916) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The HSPBP1 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s HSPBP1 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB).
FC: 1:100
IF: 1:100
WB: 1:2000. Researchers should empirically determine the suitability of the HSPBP1 hspbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The HSPBP1 hspbp1 product has the following accession number(s) (GI #112363070) (NCBI Accession #NP_036399) (Uniprot Accession #Q9NZL4). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the HSPBP1 antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant HSPBP1 protein (Right) or empty vector (Left) detected with HSPBP1 antibody)
Western Blot (WB) HSPBP1.

Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant HSPBP1 protein using HSPBP1 antibody)
Immunofluorescence (IF) HSPBP1.

Mouse monoclonal HSPBP1 antibody.

Biological Significance: HSPBP1 inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. HSPBP1 interferes with ubiquitin ation mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR. Immunogen: HSPBP1 antibody was raised in mouse using a full length recombinant protein of human HSPBP1 (NP_036399) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HSPBP1 are readily searchable from our website. Different antibodies against the same target such as HSPBP1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Bone Marrow, Brain, Heart, Liver, Lung, Lymph, Muscle, Skin tissues are correlated with this protein. HSPBP1 also interacts with the following gene(s): DNAJB1, HSPA1A, HSPA1B, HSPA2, HSPA4, HSPA5, HSPA8, PGLYRP1, STUB1, UBC. Atrophy, Brain Diseases, Carcinoma, Hepatocellular, Death, Fibrosis, Hypertension, Infertility, Male, Liver Cirrhosis are some of the diseases may be linked to HSPBP1 antibody.
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