anti-ICAM-3 antibody product blog
Tags: Antibody; Monoclonal Antibody; ICAM-3; anti-ICAM-3 antibody; ICAM-3 (MA4);
The ICAM-3 icam3 (Catalog #MBS588363) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Human ICAM-3 Mouse Monoclonal Antibody (MA4) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ICAM-3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the ICAM-3 icam3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The ICAM-3 icam3 product has the following accession number(s) (GI #167466207) (NCBI Accession #NP_002153.2) (Uniprot Accession #P32942). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Rapid clearing of apoptotic cells by phagocytes may prevent tissue damage. Studies show that ICAM-3 (also known as CD50), expressed on leukocytes, interacts with macrophages during apoptotic cell clearing (Torr et al., 2012). IQMhySan important role in the recruitment and tethering of macrophages during the process of clearing apoptotic human leukocytes, and ICAM-3 deficient cells have reduced clearance of apoptotic cells by phagocytes. This antibody, (MA4), has been shown to block the interaction of apoptotic leukocytes with macrophages/phagocytes.
Immunogen: Mammalian recombinant protein. Preservative: None. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ICAM-3 are readily searchable from our website. Different antibodies against the same target such as ICAM-3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Arthritis, Rheumatoid, Atherosclerosis, Bone Marrow Diseases, Breast Neoplasms, Hemorrhage, Inflammation, Kidney Diseases, Liver Diseases, Necrosis, Neoplasm Metastasis are some of the diseases may be linked to Human ICAM-3 Mouse Monoclonal Antibody (MA4). ICAM-3 also interacts with the following gene(s): CD209, CLEC4M, ITGAD, ITGAL, ITGB2. The following patways have been known to be associated with this gene. Blood, Brain, Embryonic Tissue, Intestine, Liver, Lung, Lymph, Lymph Node, Skin, Vascular tissues are correlated with this protein.