anti-IDE antibody product blog
Tags: Antibody; Monoclonal Antibody; IDE; anti-IDE antibody; IDE/Insulin Degrading Enzyme;
The IDE ide (Catalog #MBS8503284) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The IDE/Insulin Degrading Enzyme Mouse Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s IDE/Insulin Degrading Enzyme can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).WB: 1:1,000
IHC: 1:200. Researchers should empirically determine the suitability of the IDE ide for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IDE ide product has the following accession number(s) (GI #184556) (NCBI Accession #AAA52712.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the IDE/Insulin Degrading Enzyme Mouse Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of 1) Hela, 2) HepG2, with IDE Mouse mAb diluted at 1:2, 000. Western blot analysis of Hela, HepG2, with IDE Mouse mAb diluted at 1:2, 000.)
Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.
In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IDE are readily searchable from our website. Different antibodies against the same target such as IDE may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adenocarcinoma, Alzheimer Disease, Carcinoma, Carcinoma, Hepatocellular, Disease Models, Animal, Fibrosis, Inflammation, Liver Diseases, Liver Neoplasms, Nervous System Diseases are some of the diseases may be linked to IDE/Insulin Degrading Enzyme Mouse Monoclonal Antibody. IDE also interacts with the following gene(s): APP, CCL3, IGF2, INS, NPPB, SST. Blood, Bone, Brain, Heart, Kidney, Liver, Lung, Muscle, Skin, Vascular tissues are correlated with this protein.