anti-IkB alpha antibody product blog
Tags: Antibody; Monoclonal Antibody; IkB alpha; anti-IkB alpha antibody;
The IkB alpha nfkbia (Catalog #MBS2549084) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IkB alpha Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s IkB alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA).WB: 1:1000-1:5000
IHC: 1:50-1:500. Researchers should empirically determine the suitability of the IkB alpha nfkbia for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IkB alpha nfkbia product has the following accession number(s) (GI #13436415) (NCBI Accession #BC004983) (Uniprot Accession #P25963). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the IkB alpha Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Various lysates using IkB alpha Monoclonal Antibody at dilution of 1:3000)
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA, synonyms: IKBA, MAD-3, NFKBI). NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime.
Immunogen: Fusion Protein of IkB alpha
Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation: Unconjugated. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IkB alpha are readily searchable from our website. Different antibodies against the same target such as IkB alpha may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Drug Toxicity, Hodgkin Disease, Inflammation, Liver Diseases, Liver Neoplasms, Necrosis, Neoplasms, Neoplasms, Experimental, Nervous System Diseases, Psoriasis are some of the diseases may be linked to IkB alpha Monoclonal Antibody. The following patways have been known to be associated with this gene.